Nutraceuticals for Longer Lives

 The technology of pelletization is revolutionary for the nutraceutical sector. 

FREMONT, CA: Nutraceuticals, a preventive medicine, have significantly increased life expectancy. Nutraceuticals enable prompt treatment and, in some cases, even eliminate the need for treatment by identifying and treating diseases before they worsen or impact the patient's well-being. Additionally, it has been scientifically demonstrated that nutraceuticals can slow the aging process, ultimately leading to a longer and healthier life. In addition to these health advantages, recent research has shown that herbal nutraceuticals effectively reduce the symptoms of oxidative stress disorders. These disorders cover various illnesses, such as obesity, Alzheimer's disease, diabetes, inflammatory diseases, cancer, Parkinson's disease, allergies, and cardiovascular disorders.

Nutraceuticals are essential for improving overall health because they enrich our bodies with vital nutrients, enhancing the advantages of a balanced diet and our mental and physical well-being. Nutraceuticals are experiencing significant growth as public awareness of their benefits grows. Diverse products falling under the nutraceutical category fuel this growth, and businesses are increasingly experimenting with cutting-edge delivery strategies that draw inspiration from the pharmaceutical industry.

Tablets and capsules have traditionally dominated oral delivery systems for pharmaceuticals and nutraceuticals. These formats are changing due to adaptations driven by controlled drug delivery technologies, particularly pelletization. Similar to how it is used in pharmaceuticals, pelletization has gained traction in the nutraceutical industry as a way to alter formulation release patterns. Spherical beads, granules, or pellets of free-flowing active ingredients are produced during the procedure. These can be coated to achieve the desired modified-release properties. Pelletization has several benefits; one is combining incompatible ingredients in a single dosage form.

The process of pelletizing active ingredients can be accomplished in several ways, including extrusion spheronization, fluidized bed coating, dry powder layering, and spray congealing.

The resulting pellets can be created directly from the active nutraceutical ingredients (ANIs) or used as a foundation for adding additional active ingredients later. Base pellets come in neutral and functional varieties, with the latter improving the solubility, stability, and dissolution of ANI. The ANIs can be shielded from oxidation and deterioration and from light, moisture, and other environmental factors by being enclosed in a pellet. The pellets may offer a practical and affordable method of administering ANIs to the body.

Pellets can be effectively delivered using capsules. They function as site-specific and prolonged delivery systems and provide better tolerance. Examples include hard capsules containing caffeine pellets with a sustained release. Hard capsules containing active nutraceutical ingredients in pellet form are becoming increasingly popular.